Christopher V. DeSimone, MD, PhD, FHRS

Dr. Christopher V. DeSimone, MD, PhD, FACC, FHRS, is a cardiac electrophysiologist in the division of Heart Rhythm Services at Mayo Clinic. His PhD is in Physiology with a concentration in potassium ion-channel molecular cardiac electrophysiology. He completed a clinical and translational NIH T32 Cardiovasology research training program in combination. He is boarded in Cardiology and Clinical Cardiovascular Electrophysiology. He is the current director of Research for the division of Heart Rhythm Services at Mayo Clinic. He is also serves as Director of Marketing for the Mayo Clinic Cardiovascular Enterprise.

His clinical focus is on complex invasive electrophysiology ablation procedures. He holds the academic rank of associate professor of Medicine. He has over 400 publications, including 224 peer reviewed manuscripts. Dr. DeSimone has also garnered several awards and grant funding from his research and innovations. He has 20 issued patents pertaining to 8 different technologies, many of these being licensed.  He lectures on both a national and international level on cardiac electrophysiology.

Dr. DeSimone’s research interests include exploring innovative techniques and approaches to understand the cardiac electroanatomic and electrophysiologic basis of ventricular fibrillation. He also studies innovative approaches to mapping and ablating persistent atrial fibrillation. He also focuses on atrial fibrillation outcomes in large patient cohorts to evaluate procedural benefits and risks, and to work toward establishing best practices in optimizing procedures for patients who are underrepresented in clinical trials. He also investigates the innovation and development of catheter designs and construction for mapping and ablation of extracardiac diseases.